About site: Biotechnology and Pharmaceuticals/Pharmaceuticals/Biopharmaceuticals/Vaccines - GlobeImmune
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  About site: http://www.globeimmune.com/

Title: Biotechnology and Pharmaceuticals/Pharmaceuticals/Biopharmaceuticals/Vaccines - GlobeImmune Tharapies against hepatitis C, EGFR, the Gag protein of the HIV virus and oncogene-related mutations in human cancer. Includes technology overview, progress of clinical trials, and profile of company
Immune_Response_Corporation,_The Develops, manufactures, and markets proprietary products for treatment of human immunodeficiency virus infection and autoimmune diseases. Technical details for investors, and contacts for headquarters [more]

Intercell_AG Developer of vaccines for the prevention and treatment of infectious diseases. [more]

MedImmune,_Inc_ Develops, manufactures and markets formulations for use in immunization programs, including live virus vaccines. Includes patients guide to products, UK and US contacts, with investor relations and co [more]

Oxxon_Therapeutics Developing a portfolio of immunotherapeutics for infectious diseases and cancer using its proprietary boosting regime. Includes overview of technology, publications and corporate profile, with contact [more]

Sanofi_Pasteur Develops, manufactures and supplies vaccines for prophylaxis and therapy. Includes resource page for bacterial and viral diseases, corresponding products, company biography, links to contacts and site [more]

Serum_Institute_of_India_Ltd_ Manufacturers triple antigen for diphtheria, tetanus and pertussis, and formulations for measles, mumps, rubella and hepatitis B. Includes overview of research, quality assurance, other products, and [more]


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GlobeImmune :: Biopharma | Tarmogens | GI-5005 (misspellings: Globe Immune, GlobalImmune, Global Immune) Site Search       HomeAbout UsTechnologyProductsInvestorsClinical TrialsCareersContact Us Home About Us Technology Products Latest News GlobeImmune Hepatitis C Therapeutic Vaccine, GI-5005, Doubles Viral Clearance and Increases RVR Rates in Phase 2 Clinical TrialGlobeImmune HCV Phase 2 Four-week Clinical Trial Data for GI-5005 to be Highlighted at the AASLD President's Press ConferenceGlobeImmune Announces Late-Breaker Presentation of Interim Efficacy and Safety Data for GI-5005 at AASLD 2008 Meeting        GlobeImmune, Inc. GlobeImmune is a private biopharmaceutical company developing targeted molecular immunogens (Tarmogens®) for the treatment of cancer and infectious diseases. GlobeImmune has two products in randomized Phase 2 clinical trials. GI-5005 is being evaluated in patients with chronic hepatitis C infection (HCV), as both a front-line therapy in combination with standard of care, and as a monotherapy for second line salvage in interferon intolerant patients. GI-4000 is being evaluated in patients with pancreas, lung and colorectal cancers caused by mutations in the Ras oncogene product. To date, Tarmogens have been generally well-tolerated, and shown to generate antigen-specific T cell immune responses and improved clinical outcomes in patients. Four-week Phase 2 clinical trial data show that GI-5005, GlobeImmune’s HCV Tarmogen, doubled viral clearance overall in all major subgroups, and doubled the rapid virologic response (RVR) rate in naïve patients with high viral load. The study compared GI-5005 plus standard of care (SOC) - pegylated-interferon plus ribavirin - versus SOC alone in patients with chronic genotype 1 hepatitis C infection. The Tarmogen technology is a proprietary platform that uses recombinant yeast, engineered to express disease-specific antigens. Tarmogens naturally couple a patient’s innate immune response against the yeast, with an antigen specific T cell response against cells throughout the body that express the same protein contained in the yeast. Tarmogens can be given repeatedly, boosting the T cell response with each subsequent dose. Tarmogens are produced using fermentation processes which can be simply and economically scaled up to commercial levels. Click here to downloadthe GlobeImmune2-page Fact Sheet   Click here to downloada copy of the GI-5005AASLD 08 Phase 2 poster   Click here to downloada copy of the GI-5005AASLD 07 Phase 1b poster   llactid=13569 Copyright © GlobeImmune Inc. All Rights Reserved. Developed by Mango Media Corporation
 

Tharapies

against

hepatitis

C,

EGFR,

the

Gag

protein

of

the

HIV

virus

and

oncogene-related

mutations

in

human

cancer.

Includes

technology

overview,

progress

of

clinical

trials,

and

profile

of

company

http://www.globeimmune.com/

GlobeImmune 2009 January

dvd rental

dvd


Tharapies against hepatitis C, EGFR, the Gag protein of the HIV virus and oncogene-related mutations in human cancer. Includes technology overview, progress of clinical trials, and profile of company

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